Tissue Specificity | Strongly expressed in lung, breast, immune system and fetal tissues. |
Post Translational Modifications | |
Function | Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form a receptor complex for adrenomedullin/ADM. Together with CALCR, act as a receptor complex for calcitonin/CT/CALC. Together with CALCR, also act as a receptor complex for amylin/IAPP. |
Protein Name | Receptor Activity-Modifying Protein 2Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 2Crlr Activity-Modifying Protein 2 |
Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative ELISA Names | Receptor Activity-Modifying Protein 2 ELISA kitCalcitonin-Receptor-Like Receptor Activity-Modifying Protein 2 ELISA kitCrlr Activity-Modifying Protein 2 ELISA kitRAMP2 ELISA kit |
output | |
Information sourced from Uniprot.org