Human RAMP1 protein (Recombinant) (N-GST & C-His) (STJP010718)

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STJP010718
€410.63 - €1,796.88
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RAMP1-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RAMP1
Gene ID: 10267
Uniprot ID: RAMP1_HUMAN
Immunogen Region: Cys27-Leu119
Immunogen: Homo sapiens (Human)
Function Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form the receptor complex for the calcitonin gene-related peptides CGRP1/CALCA and CGRP2/CALCB. Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA.
Protein Name Receptor Activity-Modifying Protein 1
Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 1
Crlr Activity-Modifying Protein 1
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-419812
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Receptor Activity-Modifying Protein 1 protein
Calcitonin-Receptor-Like Receptor Activity-Modifying Protein 1 protein
Crlr Activity-Modifying Protein 1 protein
RAMP1 protein

Information sourced from Uniprot.org

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