Human RAB3D protein (Recombinant) (N-His) (STJP008759)

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STJP008759
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RAB3D-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RAB3D
Gene ID: 9545
Uniprot ID: RAB3D_HUMAN
Immunogen Region: Asp20-Glu189
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylation of Thr-86 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM and CHML.
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB3D may be involved in the insulin-induced exocytosis of GLUT4-containing vesicles in adipocytes.
Protein Name Ras-Related Protein Rab-3d
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-8873719
Cellular Localisation Cell Membrane
Lipid-Anchor
Cytoplasmic Side
Alternative Protein Names Ras-Related Protein Rab-3d protein
RAB3D protein
GOV protein
RAB16 protein

Information sourced from Uniprot.org

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