Post Translational Modifications | Farnesylated. Farnesylation is required for membrane targeting. Unfarnesylated forms are shifted into the nucleus. |
Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. |
Protein Name | Protein Tyrosine Phosphatase Type Iva 1Ptp(CaaxiProtein-Tyrosine Phosphatase 4a1Protein-Tyrosine Phosphatase Of Regenerating Liver 1Prl-1 |
Cellular Localisation | Cell MembraneLipid-AnchorEarly EndosomeEndoplasmic ReticulumCytoplasmCytoskeletonSpindleNucleusAnd Mitotic Spindle |
Alternative Protein Names | Protein Tyrosine Phosphatase Type Iva 1 proteinPtp(Caaxi proteinProtein-Tyrosine Phosphatase 4a1 proteinProtein-Tyrosine Phosphatase Of Regenerating Liver 1 proteinPrl-1 proteinPTP4A1 proteinPRL1 proteinPTPCAAX1 protein |
Information sourced from Uniprot.org