Post Translational Modifications | Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention. |
Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. |
Protein Name | Prostaglandin E2 Receptor Ep4 SubtypePge Receptor Ep4 SubtypePge2 Receptor Ep4 SubtypeProstanoid Ep4 Receptor |
Database Links | Reactome: R-HSA-391908Reactome: R-HSA-418555 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Protein Names | Prostaglandin E2 Receptor Ep4 Subtype proteinPge Receptor Ep4 Subtype proteinPge2 Receptor Ep4 Subtype proteinProstanoid Ep4 Receptor proteinPTGER4 proteinPTGER2 protein |
Information sourced from Uniprot.org