Human PTGER3 protein (Recombinant) (N-His-KSI) (STJP010467)

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STJP010467
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PTGER3-N-His-KSI protein was developed from e. coli and has a target region of N-His-KSI. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PTGER3
Gene ID: 5733
Uniprot ID: PE2R3_HUMAN
Immunogen Region: [Lys2-Ala53] & [Val113-Thr131] & [Gln198-Asn227] & [Asn308-Phe327]
Immunogen: Homo sapiens (Human)
Function Receptor for prostaglandin E2 (PGE2). The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G(i) proteins, and to an elevation of intracellular calcium. Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lipopolysaccharide (LPS). Required for normal potentiation of platelet aggregation by prostaglandin E2, and thus plays a role in the regulation of blood coagulation. Required for increased HCO3(-) secretion in the duodenum in response to mucosal acidification, and thereby contributes to the protection of the mucosa against acid-induced ulceration. Not required for normal kidney function, normal urine volume and osmolality.
Protein Name Prostaglandin E2 Receptor Ep3 Subtype
Pge Receptor Ep3 Subtype
Pge2 Receptor Ep3 Subtype
Pge2-R
Prostanoid Ep3 Receptor
Database Links Reactome: R-HSA-391908
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Prostaglandin E2 Receptor Ep3 Subtype protein
Pge Receptor Ep3 Subtype protein
Pge2 Receptor Ep3 Subtype protein
Pge2-R protein
Prostanoid Ep3 Receptor protein
PTGER3 protein

Information sourced from Uniprot.org

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