Post Translational Modifications | Degraded by the proteasome upon completion of 20S proteasome maturation. |
Function | Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. |
Protein Name | Proteasome Assembly Chaperone 2Pac-2Hepatocellular Carcinoma-Susceptibility Protein 3Tumor Necrosis Factor Superfamily Member 5-Induced Protein 1 |
Cellular Localisation | Nucleus |
Alternative Protein Names | Proteasome Assembly Chaperone 2 proteinPac-2 proteinHepatocellular Carcinoma-Susceptibility Protein 3 proteinTumor Necrosis Factor Superfamily Member 5-Induced Protein 1 proteinPSMG2 proteinHCCA3 proteinPAC2 proteinTNFSF5IP1 protein |
Information sourced from Uniprot.org