Human PSIP1 protein (Recombinant) (N-His-SUMO) (STJP008034)

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STJP008034
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PSIP1-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PSIP1
Gene ID: 11168
Uniprot ID: PSIP1_HUMAN
Immunogen Region: Thr2-Asn87
Immunogen: Homo sapiens (Human)
Post Translational Modifications Citrullinated by PADI4.
Function Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.
Protein Name Pc4 And Sfrs1-Interacting Protein
Cll-Associated Antigen Kw-7
Dense Fine Speckles 70 Kda Protein
Dfs 70
Lens Epithelium-Derived Growth Factor
Transcriptional Coactivator P75/P52
Database Links Reactome: R-HSA-162592
Reactome: R-HSA-164843
Reactome: R-HSA-175567
Reactome: R-HSA-177539
Reactome: R-HSA-180689
Reactome: R-HSA-180910
Reactome: R-HSA-9772755
Cellular Localisation Nucleus
Remains Chromatin-Associated Throughout The Cell Cycle
Alternative Protein Names Pc4 And Sfrs1-Interacting Protein protein
Cll-Associated Antigen Kw-7 protein
Dense Fine Speckles 70 Kda Protein protein
Dfs 70 protein
Lens Epithelium-Derived Growth Factor protein
Transcriptional Coactivator P75/P52 protein
PSIP1 protein
DFS70 protein
LEDGF protein
PSIP2 protein

Information sourced from Uniprot.org

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