| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from sterile PBS, pH 7.4. Normally 5 %-66 % Trehalose is added as protectants before lyophilisation. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.01 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | PSCA |
| Gene ID: | 8000 |
| Uniprot ID: | PSCA_HUMAN |
| Immunogen Region: | Leu12-Ser86 |
| Immunogen: | Recombinant Human Prostate stem cell antigen/PSCA Protein is produced by HEK293 cells expression system. The target protein is expressed with Prostate stem cell antigen/PSCA (Leu12-Ser86) fused with a His Tag at the C-terminal.. |
| Immunogen Sequence: | LLCYSCKAQVSNEDCLQVEN CTQLGEQCWTARIRAVGLLT VISKGCSLNCVDDSQDYYVG KKNITCCDTDLCNAS |
| Post Translational Modifications | N-glycosylated. |
| Function | May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs. |
| Protein Name | Prostate Stem Cell Antigen |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Prostate Stem Cell Antigen proteinPSCA proteinUNQ206 proteinPRO232 protein |
Information sourced from Uniprot.org