| Short Description : | This PRLR Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications: | ELISA |
| Reactivity: | Human |
| Sensitivity: | 0.128ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | PRLR |
| Gene ID: | 5618 |
| Uniprot ID: | PRLR_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in breast, placenta, kidney, liver and pancreas. |
| Post Translational Modifications | |
| Function | This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. |
| Protein Name | Prolactin ReceptorPrl-R |
| Database Links | Reactome: R-HSA-1170546Reactome: R-HSA-982772 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform 7: Secreted |
| Alternative ELISA Names | Prolactin Receptor ELISA kitPrl-R ELISA kitPRLR ELISA kit |
| output |
Information sourced from Uniprot.org
