Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human PRKAR2A-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | PRKAR2A |
Gene ID: | 5576 |
Uniprot ID: | KAP2_HUMAN |
Immunogen Region: | Glu266-Gln404 |
Immunogen: | Homo sapiens (Human) |
Post Translational Modifications | Phosphorylated by the activated catalytic chain. |
Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. |
Protein Name | Camp-Dependent Protein Kinase Type Ii-Alpha Regulatory Subunit |
Database Links | Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-180024Reactome: R-HSA-381676Reactome: R-HSA-432040Reactome: R-HSA-442720Reactome: R-HSA-5610787Reactome: R-HSA-9010642Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323Reactome: R-HSA-983231 |
Cellular Localisation | CytoplasmCell MembraneColocalizes With Pja2 In The Cytoplasm And The Cell Membrane |
Alternative Protein Names | Camp-Dependent Protein Kinase Type Ii-Alpha Regulatory Subunit proteinPRKAR2A proteinPKR2 proteinPRKAR2 protein |
Information sourced from Uniprot.org