| Host: | Mammalian Cells |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PRKAR1A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | PRKAR1A |
| Gene ID: | 5573 |
| Uniprot ID: | KAP0_HUMAN |
| Immunogen Region: | Glu2-Val381 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | The pseudophosphorylation site binds to the substrate-binding region of the catalytic chain, resulting in the inhibition of its activity. |
| Function | Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. |
| Protein Name | Camp-Dependent Protein Kinase Type I-Alpha Regulatory SubunitTissue-Specific Extinguisher 1Tse1 |
| Database Links | Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-180024Reactome: R-HSA-381676Reactome: R-HSA-432040Reactome: R-HSA-442720Reactome: R-HSA-5610787Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323Reactome: R-HSA-9700645Reactome: R-HSA-9725370Reactome: R-HSA-983231Reactome: R-HSA-9856530 |
| Cellular Localisation | Cell Membrane |
| Alternative Protein Names | Camp-Dependent Protein Kinase Type I-Alpha Regulatory Subunit proteinTissue-Specific Extinguisher 1 proteinTse1 proteinPRKAR1A proteinPKR1 proteinPRKAR1 proteinTSE1 protein |
Information sourced from Uniprot.org