Human PRG2/MBP protein (Recombinant) (N-His) (STJP004082)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PRG2/MBP-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PRG2 |
| Gene ID | 5553 |
| Uniprot ID | PRG2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr106-Tyr222 |
Additional Info
| Post Translational Modifications | Nitrated. |
| Function | Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. |
| Protein Name | Bone Marrow ProteoglycanBmpgProteoglycan 2 Cleaved Into - Eosinophil Granule Major Basic ProteinEmbpMbpPregnancy-Associated Major Basic Protein |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Bone Marrow Proteoglycan: SecretedThe Proform Is SecretedEosinophil Granule Major Basic Protein: Cytoplasmic VesicleSecretory VesicleThe Mature Protein Is Found In The Matrix Of The Eosinophil's Large Specific Granule (Crystalloid Core) |
| Alternative Protein Names | Bone Marrow Proteoglycan proteinBmpg proteinProteoglycan 2 Cleaved Into - Eosinophil Granule Major Basic Protein proteinEmbp proteinMbp proteinPregnancy-Associated Major Basic Protein proteinPRG2 proteinMBP protein |
Information sourced from Uniprot.org