Human PRG2/MBP protein (Recombinant) (N-His) (STJP004082)

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STJP004082
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PRG2/MBP-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PRG2
Gene ID: 5553
Uniprot ID: PRG2_HUMAN
Immunogen Region: Thr106-Tyr222
Immunogen: Homo sapiens (Human)
Post Translational Modifications Nitrated.
Function Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
Protein Name Bone Marrow Proteoglycan
Bmpg
Proteoglycan 2 Cleaved Into - Eosinophil Granule Major Basic Protein
Embp
Mbp
Pregnancy-Associated Major Basic Protein
Database Links Reactome: R-HSA-6798695
Cellular Localisation Bone Marrow Proteoglycan: Secreted
The Proform Is Secreted
Eosinophil Granule Major Basic Protein: Cytoplasmic Vesicle
Secretory Vesicle
The Mature Protein Is Found In The Matrix Of The Eosinophil's Large Specific Granule (Crystalloid Core)
Alternative Protein Names Bone Marrow Proteoglycan protein
Bmpg protein
Proteoglycan 2 Cleaved Into - Eosinophil Granule Major Basic Protein protein
Embp protein
Mbp protein
Pregnancy-Associated Major Basic Protein protein
PRG2 protein
MBP protein

Information sourced from Uniprot.org

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