Human PRDX5 protein (Recombinant) (N-His) (STJP006607)

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STJP006607
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PRDX5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PRDX5
Gene ID: 25824
Uniprot ID: PRDX5_HUMAN
Immunogen Region: Met1-Asp162
Immunogen: Homo sapiens (Human)
Post Translational Modifications S-palmitoylated. Palmitoylation occurs on the active site, inhibiting its reactivity.therefore PRDX5 palmitoylation status determines its antioxidant capacity. Isoform Mitochondrial: S-palmitoylated. Depalmitoylated by ABHD10.
Function Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Protein Name Peroxiredoxin-5 - Mitochondrial
Alu Corepressor 1
Antioxidant Enzyme B166
Aoeb166
Liver Tissue 2d-Page Spot 71b
Plp
Peroxiredoxin V
Prx-V
Peroxisomal Antioxidant Enzyme
Tpx Type Vi
Thioredoxin Peroxidase Pmp20
Thioredoxin-Dependent Peroxiredoxin 5
Database Links Reactome: R-HSA-3299685
Reactome: R-HSA-5628897 P30044-2
Cellular Localisation Isoform Mitochondrial: Mitochondrion
Isoform Cytoplasmic+Peroxisomal: Cytoplasm
Peroxisome Matrix
Imported Into Peroxisomes Via Peroxisomal Targeting Signal 1 Receptor Pex5
Alternative Protein Names Peroxiredoxin-5 - Mitochondrial protein
Alu Corepressor 1 protein
Antioxidant Enzyme B166 protein
Aoeb166 protein
Liver Tissue 2d-Page Spot 71b protein
Plp protein
Peroxiredoxin V protein
Prx-V protein
Peroxisomal Antioxidant Enzyme protein
Tpx Type Vi protein
Thioredoxin Peroxidase Pmp20 protein
Thioredoxin-Dependent Peroxiredoxin 5 protein
PRDX5 protein
ACR1 protein
SBBI10 protein

Information sourced from Uniprot.org

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