Human PRDX4 protein (Recombinant) (N-His) (STJP005295)

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STJP005295
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PRDX4-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PRDX4
Gene ID: 10549
Uniprot ID: PRDX4_HUMAN
Immunogen Region: Leu6-Trp249
Immunogen: Homo sapiens (Human)
Function Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
Protein Name Peroxiredoxin-4
Antioxidant Enzyme Aoe372
Aoe37-2
Peroxiredoxin Iv
Prx-Iv
Thioredoxin Peroxidase Ao372
Thioredoxin-Dependent Peroxide Reductase A0372
Thioredoxin-Dependent Peroxiredoxin 4
Database Links Reactome: R-HSA-6798695
Cellular Localisation Cytoplasm
Endoplasmic Reticulum
Cotranslationally Translocated To And Retained Within The Endoplasmic Reticulum
A Small Fraction Of The Protein Is Cytoplasmic
Alternative Protein Names Peroxiredoxin-4 protein
Antioxidant Enzyme Aoe372 protein
Aoe37-2 protein
Peroxiredoxin Iv protein
Prx-Iv protein
Thioredoxin Peroxidase Ao372 protein
Thioredoxin-Dependent Peroxide Reductase A0372 protein
Thioredoxin-Dependent Peroxiredoxin 4 protein
PRDX4 protein

Information sourced from Uniprot.org

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