Human PRDX1 protein (Recombinant) (N-His) (STJP007473)

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STJP007473
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PRDX1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PRDX1
Gene ID: 5052
Uniprot ID: PRDX1_HUMAN
Immunogen Region: Lys16-Lys199
Immunogen: Homo sapiens (Human)
Function Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.
Protein Name Peroxiredoxin-1
Natural Killer Cell-Enhancing Factor A
Nkef-A
Proliferation-Associated Gene Protein
Pag
Thioredoxin Peroxidase 2
Thioredoxin-Dependent Peroxide Reductase 2
Thioredoxin-Dependent Peroxiredoxin 1
Database Links Reactome: R-HSA-3299685
Reactome: R-HSA-5628897
Reactome: R-HSA-8862803
Reactome: R-HSA-9818027
Cellular Localisation Cytoplasm
Melanosome
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Protein Names Peroxiredoxin-1 protein
Natural Killer Cell-Enhancing Factor A protein
Nkef-A protein
Proliferation-Associated Gene Protein protein
Pag protein
Thioredoxin Peroxidase 2 protein
Thioredoxin-Dependent Peroxide Reductase 2 protein
Thioredoxin-Dependent Peroxiredoxin 1 protein
PRDX1 protein
PAGA protein
PAGB protein
TDPX2 protein

Information sourced from Uniprot.org