Human PPP2R2A protein (Recombinant) (N-His) (STJP010023)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PPP2R2A-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PPP2R2A |
| Gene ID | 5520 |
| Uniprot ID | 2ABA_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Asn447 |
Additional Info
| Function | Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. Involved in chromosome clustering during late mitosis by mediating dephosphorylation of MKI67. Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint. |
| Protein Name | Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Alpha IsoformPp2a Subunit B Isoform B55-AlphaB55Pp2a Subunit B Isoform Pr55-AlphaPp2a Subunit B Isoform R2-AlphaPp2a Subunit B Isoform Alpha |
| Database Links | Reactome: R-HSA-2995383Reactome: R-HSA-69231Reactome: R-HSA-69273Reactome: R-HSA-975957Reactome: R-HSA-9860927 |
| Cellular Localisation | |
| Alternative Protein Names | Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Alpha Isoform proteinPp2a Subunit B Isoform B55-Alpha proteinB55 proteinPp2a Subunit B Isoform Pr55-Alpha proteinPp2a Subunit B Isoform R2-Alpha proteinPp2a Subunit B Isoform Alpha proteinPPP2R2A protein |
Information sourced from Uniprot.org