Human PPP2R2A protein (Recombinant) (N-His) (STJP010023)

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STJP010023
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PPP2R2A-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PPP2R2A
Gene ID: 5520
Uniprot ID: 2ABA_HUMAN
Immunogen Region: Met1-Asn447
Immunogen: Homo sapiens (Human)
Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint.
Protein Name Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Alpha Isoform
Pp2a Subunit B Isoform B55-Alpha
Pp2a Subunit B Isoform Pr55-Alpha
Pp2a Subunit B Isoform R2-Alpha
Pp2a Subunit B Isoform Alpha
Database Links Reactome: R-HSA-2995383
Reactome: R-HSA-69231
Reactome: R-HSA-69273
Reactome: R-HSA-975957
Alternative Protein Names Serine/Threonine-Protein Phosphatase 2a 55 Kda Regulatory Subunit B Alpha Isoform protein
Pp2a Subunit B Isoform B55-Alpha protein
Pp2a Subunit B Isoform Pr55-Alpha protein
Pp2a Subunit B Isoform R2-Alpha protein
Pp2a Subunit B Isoform Alpha protein
PPP2R2A protein

Information sourced from Uniprot.org

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