| Host: | E.coli |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PPP1R14A-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 0.2mM EDTA, 1mM DTT, 10% Glycerol, pH 8.0. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | PPP1R14A |
| Gene ID: | 94274 |
| Uniprot ID: | PP14A_HUMAN |
| Immunogen Region: | Met1-Pro147 |
| Immunogen: | Homo sapiens (Human) |
| Function | Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 14a17 Kda Pkc-Potentiated Inhibitory Protein Of Pp1Protein Kinase C-Potentiated Inhibitor Protein Of 17 KdaCpi-17 |
| Database Links | Reactome: R-HSA-5625740 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Protein Phosphatase 1 Regulatory Subunit 14a protein17 Kda Pkc-Potentiated Inhibitory Protein Of Pp1 proteinProtein Kinase C-Potentiated Inhibitor Protein Of 17 Kda proteinCpi-17 proteinPPP1R14A proteinCPI17 proteinPPP1INL protein |
Information sourced from Uniprot.org