Human PPM1B protein (Recombinant) (N-His) (STJP010744)

SKU:
STJP010744
€410.63 - €1,796.88
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PPM1B-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PPM1B
Gene ID: 5495
Uniprot ID: PPM1B_HUMAN
Immunogen Region: Met1-Asn371
Immunogen: Homo sapiens (Human)
Post Translational Modifications Isgylation negatively regulates its activity. N-myristoylation is essential for the recognition of its substrates for dephosphorylation.
Function Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Protein Name Protein Phosphatase 1b
Protein Phosphatase 2c Isoform Beta
Pp2c-Beta
Database Links Reactome: R-HSA-1169408
Reactome: R-HSA-9700645
Reactome: R-HSA-9725370
Cellular Localisation Cytoplasm
Cytosol
Membrane
Lipid-Anchor
Weakly Associates At The Membrane And N-Myristoylation Mediates The Membrane Localization
Alternative Protein Names Protein Phosphatase 1b protein
Protein Phosphatase 2c Isoform Beta protein
Pp2c-Beta protein
PPM1B protein
PP2CB protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP002980 Human KLHL20 protein (Recombinant) (N-His) (STJP002980) HEK293 cells
STJP003027 Human CCL3L1 protein (Recombinant) (N-His) (STJP003027) HEK293 cells
STJP003488 Human CFD protein (Recombinant) (N-His) (STJP003488) E. coli

Related Products

!