| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PPL-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | PPL |
| Gene ID: | 5493 |
| Uniprot ID: | PEPL_HUMAN |
| Immunogen Region: | Glu1439-Gly1716 |
| Immunogen: | Homo sapiens (Human) |
| Function | Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling. |
| Protein Name | Periplakin190 Kda Paraneoplastic Pemphigus Antigen195 Kda Cornified Envelope Precursor Protein |
| Database Links | Reactome: R-HSA-6809371Reactome: R-HSA-8851680 |
| Cellular Localisation | Cell JunctionDesmosomeCytoplasmCytoskeletonCell Membrane |
| Alternative Protein Names | Periplakin protein190 Kda Paraneoplastic Pemphigus Antigen protein195 Kda Cornified Envelope Precursor Protein proteinPPL proteinKIAA0568 protein |
Information sourced from Uniprot.org