Human POSTN/OSF-2 protein (Recombinant-Active) (C-His) (STJP012113)

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STJP012113-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human POSTN/OSF-2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: POSTN
Gene ID: 10631
Uniprot ID: POSTN_HUMAN
Immunogen Region: Asn22-Gln836
Immunogen: Homo sapiens (Human)
Post Translational Modifications Gamma-carboxylation is controversial. Gamma-carboxyglutamated.gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation.this may be required for calcium binding. According to a more recent report, does not contain vitamin K-dependent gamma-carboxyglutamate residues.
Function Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX.
Protein Name Periostin
Pn
Osteoblast-Specific Factor 2
Osf-2
Cellular Localisation Golgi Apparatus
Secreted
Extracellular Space
Extracellular Matrix
Colocalizes With Bmp1 In The Golgi
Alternative Protein Names Periostin protein
Pn protein
Osteoblast-Specific Factor 2 protein
Osf-2 protein
POSTN protein
OSF2 protein

Information sourced from Uniprot.org

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