| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PON3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | PON3 |
| Gene ID: | 5446 |
| Uniprot ID: | PON3_HUMAN |
| Immunogen Region: | Leu22-Leu354 |
| Immunogen: | Homo sapiens (Human) |
| Function | Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents. |
| Protein Name | Serum Paraoxonase/Lactonase 3 |
| Database Links | Reactome: R-HSA-2142688Reactome: R-HSA-9754706 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Protein Names | Serum Paraoxonase/Lactonase 3 proteinPON3 protein |
Information sourced from Uniprot.org
