Human PON1 protein (Recombinant) (N-His) (STJP004449)

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STJP004449
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PON1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PON1
Gene ID: 5444
Uniprot ID: PON1_HUMAN
Immunogen Region: Gln35-Val206
Immunogen: Homo sapiens (Human)
Post Translational Modifications Glycosylated. The signal sequence is not cleaved. Present in two forms, form B contains a disulfide bond, form A does not.
Function Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Protein Name Serum Paraoxonase/Arylesterase 1
Pon 1
Aromatic Esterase 1
A-Esterase 1
K-45
Serum Aryldialkylphosphatase 1
Database Links Reactome: R-HSA-2142688
Reactome: R-HSA-9754706
Cellular Localisation Secreted
Extracellular Space
Alternative Protein Names Serum Paraoxonase/Arylesterase 1 protein
Pon 1 protein
Aromatic Esterase 1 protein
A-Esterase 1 protein
K-45 protein
Serum Aryldialkylphosphatase 1 protein
PON1 protein
PON protein

Information sourced from Uniprot.org

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