Human POMT1 protein (Recombinant) (N-His) (STJP006292)

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STJP006292
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human POMT1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: POMT1
Gene ID: 10585
Uniprot ID: POMT1_HUMAN
Immunogen Region: Pro318-His513
Immunogen: Homo sapiens (Human)
Function Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins.
Protein Name Protein O-Mannosyl-Transferase 1
Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1
Database Links Reactome: R-HSA-5083629
Reactome: R-HSA-5083633
Reactome: R-HSA-5173105
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Protein O-Mannosyl-Transferase 1 protein
Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 1 protein
POMT1 protein

Information sourced from Uniprot.org

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