Human POFUT2 protein (Recombinant) (N-His) (STJP009742)

SKU:
STJP009742
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human POFUT2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: POFUT2
Gene ID: 23275
Uniprot ID: OFUT2_HUMAN
Immunogen Region: Pro53-Tyr167
Immunogen: Homo sapiens (Human)
Function Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X-X-S/T-C2 of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS, the thrombospondin (TSP) and spondin families (Probable). Required for the proper secretion of ADAMTS family members such as ADAMTSL1 and ADAMTS13. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm.
Protein Name Gdp-Fucose Protein O-Fucosyltransferase 2
Peptide-O-Fucosyltransferase 2
O-Fuct-2
Database Links Reactome: R-HSA-5173214
Cellular Localisation Endoplasmic Reticulum
Golgi Apparatus
Mainly Located In The Endoplasmic Reticulum
Alternative Protein Names Gdp-Fucose Protein O-Fucosyltransferase 2 protein
Peptide-O-Fucosyltransferase 2 protein
O-Fuct-2 protein
POFUT2 protein
C21orf80 protein
FUT13 protein
KIAA0958 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005172 Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172) E. coli
STJP004723 Human WAS protein (Recombinant) (N-His) (STJP004723) E. coli
STJP003644 Human ALDOA protein (Recombinant) (N-His) (STJP003644) E. coli
STJP003667 Human KRT1 protein (Recombinant) (N-His) (STJP003667) E. coli
STJP003695 Human ALDH2 protein (Recombinant) (N-His) (STJP003695) E. coli

Related Products

!