| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PNP-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | PNP |
| Gene ID: | 4860 |
| Uniprot ID: | PNPH_HUMAN |
| Immunogen Region: | Met1-Ser289 |
| Immunogen: | Homo sapiens (Human) |
| Function | Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine. |
| Protein Name | Purine Nucleoside PhosphorylasePnpInosine PhosphorylaseInosine-Guanosine Phosphorylase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-74217Reactome: R-HSA-74259Reactome: R-HSA-9735763Reactome: R-HSA-9755088 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Purine Nucleoside Phosphorylase proteinPnp proteinInosine Phosphorylase proteinInosine-Guanosine Phosphorylase proteinPNP proteinNP protein |
Information sourced from Uniprot.org