| Short Description : | Recombinant-Human PNMT-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PNMT |
| Gene ID: | 5409 |
| Uniprot ID: | PNMT_HUMAN |
| Accession Number: | NP_002677 |
| Immunogen: | Human |
| Immunogen Region: | 1-282aa |
| Immunogen Sequence: | MSGADRSPNA GAAPDSAPGQ AAVASAYQRF EPRAYLRNNY APPRGDLCNP NGVGPWKLRC LAQTFATGEV SGRTLIDIGS GPTVYQLLSA CSHFEDITMT DFLEVNRQEL GRWLQEEPGA FNWSMYSQHA CLIEGKGECW QDKERQLRAR VKRVLPIDVH QPQPLGAGSP APLPADALVS AFCLEAVSPD LASFQRALDH ITTLLRPGGH LLLIGALEES WYLAGEAR |
| Function | Catalyzes the transmethylation of nonepinephrine (noradrenaline) to form epinephrine (adrenaline), using S-adenosyl-L-methionine as the methyl donor. Other substrates include phenylethanolamine and octopamine. Also methylates normetanephrine. |
| Protein Name | Phenylethanolamine N-MethyltransferasePnmtaseNoradrenaline N-Methyltransferase |
| Database Links | Reactome: R-HSA-209905 |
| Cellular Localisation | |
| Alternative Protein Names | Phenylethanolamine N-Methyltransferase proteinPnmtase proteinNoradrenaline N-Methyltransferase proteinPNMT proteinPENT protein |
Information sourced from Uniprot.org
