| Host: | E.coli |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PMVK-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | PMVK |
| Gene ID: | 10654 |
| Uniprot ID: | PMVK_HUMAN |
| Immunogen Region: | Met1-Leu192 |
| Immunogen: | Homo sapiens (Human) |
| Function | Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites. |
| Protein Name | Phosphomevalonate KinasePmkaseHpmk |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Phosphomevalonate Kinase proteinPmkase proteinHpmk proteinPMVK proteinPMKI protein |
Information sourced from Uniprot.org