Human PLSCR4 protein (Recombinant) (N-His) (STJP006080)

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STJP006080
£222.50 - £1,177.50
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PLSCR4-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PLSCR4
Gene ID: 57088
Uniprot ID: PLS4_HUMAN
Immunogen Region: Met1-Lys303
Immunogen: Homo sapiens (Human)
Function Catalyzes metal ion-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane and participates in the redistribution of phospholipids between membrane leaflets. Metal ions bind to the calcium-binding site and induce conformation change in the protein. Has a greater affi nity for Ca(2+) than Mg(2+) and Zn(2+).
Protein Name Phospholipid Scramblase 4
Pl Scramblase 4
Ca(2+-Dependent Phospholipid Scramblase 4
Cell Growth-Inhibiting Gene 43 Protein
Tra1
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Lipid-Anchor
Cytoplasmic Side
Nucleus
Palmitoylation Regulates Its Localization To The Cell Membrane Or The Nucleus
Trafficking To The Cell Membrane Is Dependent Upon Palmitoylation Whereas In The Absence Of Palmitoylation
Localizes To The Nucleus
Alternative Protein Names Phospholipid Scramblase 4 protein
Pl Scramblase 4 protein
Ca(2+-Dependent Phospholipid Scramblase 4 protein
Cell Growth-Inhibiting Gene 43 Protein protein
Tra1 protein
PLSCR4 protein
GIG43 protein

Information sourced from Uniprot.org