| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PLIN2-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | PLIN2 |
| Gene ID: | 123 |
| Uniprot ID: | PLIN2_HUMAN |
| Immunogen Region: | Ala5-Tyr232 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Acylated.primarily with C14, C16 and C18 fatty acids. Phosphorylation at Tyr-232 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis. Polyubiquitination of Nt-acetylatable A-PLIN2 by MARCHF6 lead to degradation by 26S proteasomes. |
| Function | Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets. |
| Protein Name | Perilipin-2AdipophilinAdipose Differentiation-Related ProteinAdrp |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-9613354Reactome: R-HSA-9613829Reactome: R-HSA-9615710Reactome: R-HSA-9841922 |
| Cellular Localisation | MembranePeripheral Membrane ProteinLipid Droplet |
| Alternative Protein Names | Perilipin-2 proteinAdipophilin proteinAdipose Differentiation-Related Protein proteinAdrp proteinPLIN2 proteinADFP protein |
Information sourced from Uniprot.org