| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.053ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This PLIN1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | PLIN1 |
| Gene ID: | 5346 |
| Uniprot ID: | PLIN1_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Detected in adipocytes from white adipose tissue (at protein level). Detected in visceral adipose tissue and mammary gland. |
| Post Translational Modifications | Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet. |
| Function | Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels. |
| Protein Name | Perilipin-1 Lipid Droplet-Associated Protein |
| Database Links | Reactome: R-HSA-163560 Reactome: R-HSA-381340 Reactome: R-HSA-9031528 |
| Cellular Localisation | Endoplasmic Reticulum Lipid Droplet Lipid Droplet Surface-Associated |
| Alternative ELISA Names | Perilipin-1 ELISA kit Lipid Droplet-Associated Protein ELISA kit PLIN1 ELISA kit PERI ELISA kit PLIN ELISA kit |
| output |
Information sourced from Uniprot.org