| Tissue Specificity | Detected in adipocytes from white adipose tissue (at protein level). Detected in visceral adipose tissue and mammary gland. |
| Post Translational Modifications | Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet. |
| Function | Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels. |
| Protein Name | Perilipin-1Lipid Droplet-Associated Protein |
| Database Links | Reactome: R-HSA-163560Reactome: R-HSA-381340Reactome: R-HSA-9031528 |
| Cellular Localisation | Endoplasmic ReticulumLipid DropletLipid Droplet Surface-Associated |
| Alternative ELISA Names | Perilipin-1 ELISA kitLipid Droplet-Associated Protein ELISA kitPLIN1 ELISA kitPERI ELISA kitPLIN ELISA kit |
| output | |
Information sourced from Uniprot.org
