Human PLCD3 protein (Recombinant) (N-His) (STJP005690)

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STJP005690
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PLCD3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PLCD3
Gene ID: 113026
Uniprot ID: PLCD3_HUMAN
Immunogen Region: Leu528-Ser789
Immunogen: Homo sapiens (Human)
Function Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow. Regulates neurite outgrowth through the inhibition of RhoA/Rho kinase signaling.
Protein Name 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Delta-3
Phosphoinositide Phospholipase C-Delta-3
Phospholipase C-Delta-3
Plc-Delta-3
Database Links Reactome: R-HSA-1855204
Cellular Localisation Membrane
Peripheral Membrane Protein
Cytoplasm
Cleavage Furrow
Localizes At The Cleavage Furrow During Cytokinesis
Alternative Protein Names 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Delta-3 protein
Phosphoinositide Phospholipase C-Delta-3 protein
Phospholipase C-Delta-3 protein
Plc-Delta-3 protein
PLCD3 protein
KIAA1964 protein

Information sourced from Uniprot.org

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