Host: | E. coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human PIH1D1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | PIH1D1 |
Gene ID: | 55011 |
Uniprot ID: | PIHD1_HUMAN |
Immunogen Region: | Glu15-Ser181 |
Immunogen: | Homo sapiens (Human) |
Function | Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles. Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription. Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1. Positively regulates the assembly and activity of the mTORC1 complex. |
Protein Name | Pih1 Domain-Containing Protein 1Nucleolar Protein 17 Homolog |
Cellular Localisation | Nucleus |
Alternative Protein Names | Pih1 Domain-Containing Protein 1 proteinNucleolar Protein 17 Homolog proteinPIH1D1 proteinNOP17 protein |
Information sourced from Uniprot.org