Human PHOX2B protein (Recombinant) (N-His-SUMO) (STJP008789)

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STJP008789
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PHOX2B-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PHOX2B
Gene ID: 8929
Uniprot ID: PHX2B_HUMAN
Immunogen Region: Thr106-Gly173
Immunogen: Homo sapiens (Human)
Function Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.
Protein Name Paired Mesoderm Homeobox Protein 2b
Neuroblastoma Phox
Nbphox
Phox2b Homeodomain Protein
Paired-Like Homeobox 2b
Cellular Localisation Nucleus
Alternative Protein Names Paired Mesoderm Homeobox Protein 2b protein
Neuroblastoma Phox protein
Nbphox protein
Phox2b Homeodomain Protein protein
Paired-Like Homeobox 2b protein
PHOX2B protein
PMX2B protein

Information sourced from Uniprot.org