Function | Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. |
Protein Name | Paired Mesoderm Homeobox Protein 2bNeuroblastoma PhoxNbphoxPhox2b Homeodomain ProteinPaired-Like Homeobox 2b |
Cellular Localisation | Nucleus |
Alternative Protein Names | Paired Mesoderm Homeobox Protein 2b proteinNeuroblastoma Phox proteinNbphox proteinPhox2b Homeodomain Protein proteinPaired-Like Homeobox 2b proteinPHOX2B proteinPMX2B protein |
Information sourced from Uniprot.org