| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PHOX2B-N-GST & C-His protein was developed from e.coli and has a target region of N-GST & C-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | Please contact us for further information. |
| Gene Symbol: | PHOX2B |
| Gene ID: | 8929 |
| Uniprot ID: | PHX2B_HUMAN |
| Immunogen Region: | Thr106-Gly173 |
| Immunogen: | Homo sapiens (Human) |
| Function | Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. |
| Protein Name | Paired Mesoderm Homeobox Protein 2bNeuroblastoma PhoxNbphoxPhox2b Homeodomain ProteinPaired-Like Homeobox 2b |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Paired Mesoderm Homeobox Protein 2b proteinNeuroblastoma Phox proteinNbphox proteinPhox2b Homeodomain Protein proteinPaired-Like Homeobox 2b proteinPHOX2B proteinPMX2B protein |
Information sourced from Uniprot.org