Human PGAM1 protein (Recombinant) (N-His) (STJP004226)

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STJP004226
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PGAM1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PGAM1
Gene ID: 5223
Uniprot ID: PGAM1_HUMAN
Immunogen Region: Ala2-Lys254
Immunogen: Homo sapiens (Human)
Post Translational Modifications Acetylated at Lys-253, Lys-253 and Lys-254 under high glucose condition. Acetylation increases catalytic activity. Under glucose restriction SIRT1 levels dramatically increase and it deacetylates the enzyme.
Function Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglyceratea crucial step in glycolysis, by using 2,3-bisphosphoglycerate. Also catalyzes the interconversion of (2R)-2,3-bisphosphoglycerate and (2R)-3-phospho-glyceroyl phosphate.
Protein Name Phosphoglycerate Mutase 1
Bpg-Dependent Pgam 1
Phosphoglycerate Mutase Isozyme B
Pgam-B
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-70171
Reactome: R-HSA-70263
Alternative Protein Names Phosphoglycerate Mutase 1 protein
Bpg-Dependent Pgam 1 protein
Phosphoglycerate Mutase Isozyme B protein
Pgam-B protein
PGAM1 protein
PGAMA protein
CDABP0006 protein

Information sourced from Uniprot.org

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