| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PFN2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | PFN2 |
| Gene ID: | 5217 |
| Uniprot ID: | PROF2_HUMAN |
| Immunogen Region: | Gln5-Phe140 |
| Immunogen: | Homo sapiens (Human) |
| Function | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. |
| Protein Name | Profilin-2Profilin Ii |
| Database Links | Reactome: R-HSA-376176Reactome: R-HSA-5663220 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Protein Names | Profilin-2 proteinProfilin Ii proteinPFN2 protein |
Information sourced from Uniprot.org