Human PEA15 protein (Recombinant) (Tag free) (STJP014634)

Name: Human PEA15 protein (Recombinant) (Tag free) (STJP014634)
SKU: STJP014634-100
Price: 503.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP014634-100

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Short Description	Recombinant-Human PEA15-Tag free protein was developed from e.coli and has a target region of Tag free. For use in research applications.
Applications	ELISA/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Post Translational Modifications	Phosphorylated by protein kinase C and calcium-calmodulin-dependent protein kinase. These phosphorylation events are modulated by neurotransmitters or hormones.
Function	Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.
Protein Name	Astrocytic Phosphoprotein Pea-15 15 Kda Phosphoprotein Enriched In Astrocytes Phosphoprotein Enriched In Diabetes Ped
Database Links	Reactome: R-HSA-112409 Reactome: R-HSA-5673001
Cellular Localisation	Cytoplasm Associated With Microtubules
Alternative Protein Names	Astrocytic Phosphoprotein Pea-15 protein 15 Kda Phosphoprotein Enriched In Astrocytes protein Phosphoprotein Enriched In Diabetes protein Ped protein PEA15 protein

Information sourced from Uniprot.org