Human PEA15 protein (Recombinant) (N-His) (STJP016167)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PEA15-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | PEA15 |
| Gene ID | 8682 |
| Uniprot ID | PEA15_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Ala130 |
Additional Info
| Post Translational Modifications | Phosphorylated by protein kinase C and calcium-calmodulin-dependent protein kinase. These phosphorylation events are modulated by neurotransmitters or hormones. |
| Function | Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface. |
| Protein Name | Astrocytic Phosphoprotein Pea-1515 Kda Phosphoprotein Enriched In AstrocytesPhosphoprotein Enriched In DiabetesPed |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-5673001 |
| Cellular Localisation | CytoplasmAssociated With Microtubules |
| Alternative Protein Names | Astrocytic Phosphoprotein Pea-15 protein15 Kda Phosphoprotein Enriched In Astrocytes proteinPhosphoprotein Enriched In Diabetes proteinPed proteinPEA15 protein |
Information sourced from Uniprot.org