Function | Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. |
Protein Name | Pyruvate Dehydrogenase Protein X Component - MitochondrialDihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase ComplexE3-Binding ProteinE3bpLipoyl-Containing Pyruvate Dehydrogenase Complex Component XProx |
Database Links | Reactome: R-HSA-204174Reactome: R-HSA-5362517Reactome: R-HSA-9861559 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Protein Names | Pyruvate Dehydrogenase Protein X Component - Mitochondrial proteinDihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase Complex proteinE3-Binding Protein proteinE3bp proteinLipoyl-Containing Pyruvate Dehydrogenase Complex Component X proteinProx proteinPDHX proteinPDX1 protein |
Information sourced from Uniprot.org