Human PCBP1 protein (Recombinant) (N-His) (STJP007992)

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STJP007992
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PCBP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PCBP1
Gene ID: 5093
Uniprot ID: PCBP1_HUMAN
Immunogen Region: Asn11-Ser173
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated.lowers poly(rC)-binding activity.
Function Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing. (Microbial infection) In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD.
Protein Name Poly(Rc-Binding Protein 1
Alpha-Cp1
Heterogeneous Nuclear Ribonucleoprotein E1
Hnrnp E1
Nucleic Acid-Binding Protein Sub2.3
Database Links Reactome: R-HSA-72163
Reactome: R-HSA-72203
Cellular Localisation Nucleus
Cytoplasm
Loosely Bound In The Nucleus
May Shuttle Between The Nucleus And The Cytoplasm
Alternative Protein Names Poly(Rc-Binding Protein 1 protein
Alpha-Cp1 protein
Heterogeneous Nuclear Ribonucleoprotein E1 protein
Hnrnp E1 protein
Nucleic Acid-Binding Protein Sub2.3 protein
PCBP1 protein

Information sourced from Uniprot.org

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