Human PCBD1 protein (Recombinant) (His-Tag) (STJP016839)

Name: Human PCBD1 protein (Recombinant) (His-Tag) (STJP016839)
SKU: STJP016839
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP016839

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Short Description	Recombinant-Human PCBD1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	PCBD1
Gene ID	5092
Uniprot ID	PHS_HUMAN
Accession Number	NP_000272
Immunogen	Human
Immunogen Region	1-104aa
Immunogen Sequence	MAGKAHRLSA EERDQLLPNL RAVGWNELEG RDAIFKQFHF KDFNRAFGFM TRVALQAEKL DHHPEWFNVY NKVHITLSTH ECAGLSERDI NLASFIEQVA VSMT

Function	Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. Also acts as a coactivator for HNF1B-dependent transcription.
Protein Name	Pterin-4-Alpha-Carbinolamine Dehydratase Phs 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha Dcoh Dimerization Cofactor Of Hnf1 Phenylalanine Hydroxylase-Stimulating Protein Pterin Carbinolamine Dehydratase Pcd
Database Links	Reactome: R-HSA-8964208
Cellular Localisation	Cytoplasm Nucleus Recruited To The Nucleus Through The Interaction With Hnf1b
Alternative Protein Names	Pterin-4-Alpha-Carbinolamine Dehydratase protein Phs protein 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase protein Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha protein Dcoh protein Dimerization Cofactor Of Hnf1 protein Phenylalanine Hydroxylase-Stimulating Protein protein Pterin Carbinolamine Dehydratase protein Pcd protein PCBD1 protein DCOH protein PCBD protein

Information sourced from Uniprot.org