| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PBRM1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | PBRM1 |
| Gene ID: | 55193 |
| Uniprot ID: | PB1_HUMAN |
| Immunogen Region: | His1152-Gly1273 |
| Immunogen: | Homo sapiens (Human) |
| Function | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. |
| Protein Name | Protein Polybromo-1Hpb1Brg1-Associated Factor 180Baf180Polybromo-1d |
| Database Links | Reactome: R-HSA-3214858Reactome: R-HSA-8939243 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Protein Polybromo-1 proteinHpb1 proteinBrg1-Associated Factor 180 proteinBaf180 proteinPolybromo-1d proteinPBRM1 proteinBAF180 proteinPB1 protein |
Information sourced from Uniprot.org