| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PAPPA2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | PAPPA2 |
| Gene ID: | 60676 |
| Uniprot ID: | PAPP2_HUMAN |
| Immunogen Region: | Ser234-Cys1396 |
| Immunogen: | Homo sapiens (Human) |
| Function | Metalloproteinase which specifically cleaves insulin-like growth factor binding protein (IGFBP)-5 at the '163-Ser-|-Lys-164' bond. Shows limited proteolysis toward IGFBP-3. |
| Protein Name | Pappalysin-2Pregnancy-Associated Plasma Protein A2Papp-A2Pregnancy-Associated Plasma Protein E1Papp-E |
| Database Links | Reactome: R-HSA-381426 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Pappalysin-2 proteinPregnancy-Associated Plasma Protein A2 proteinPapp-A2 proteinPregnancy-Associated Plasma Protein E1 proteinPapp-E proteinPAPPA2 proteinPLAC3 protein |
Information sourced from Uniprot.org