Human PAOX protein (Recombinant) (N-His) (STJP006390)

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STJP006390
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PAOX-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PAOX
Gene ID: 196743
Uniprot ID: PAOX_HUMAN
Immunogen Region: Val242-Gly484
Immunogen: Homo sapiens (Human)
Function Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Protein Name Peroxisomal N(1-Acetyl-Spermine/Spermidine Oxidase
Polyamine Oxidase
Database Links Reactome: R-HSA-141334
Reactome: R-HSA-351200
Reactome: R-HSA-9033241
Cellular Localisation Peroxisome
Cytoplasm
Alternative Protein Names Peroxisomal N(1-Acetyl-Spermine/Spermidine Oxidase protein
Polyamine Oxidase protein
PAOX protein
PAO protein
UNQ1923 protein
PRO4398 protein

Information sourced from Uniprot.org

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