Human PADI6 (Peptidyl Arginine Deiminase Type VI) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017634)

Human PADI6 (Peptidyl Arginine Deiminase Type VI) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017634)

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STJE0017634
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.062ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This PADI6 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: PADI6
Gene ID: 353238
Uniprot ID: PADI6_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in oocytes and weakly expressed in other somatic tissues.
Post Translational Modifications Phosphorylation at Ser-10, possibly by RSK-type kinases, and Ser-446 creates binding sites for 14-3-3 proteins.
Function Structural constituent of cytoplasmic lattices, which plays a key role in early embryonic development. Cytoplasmic lattices consist in fibrous structures found in the cytoplasm of oocytes and preimplantation embryos. They are required to store maternal proteins critical for embryonic development, such as ribosomal proteins and proteins that control epigenetic reprogramming of the preimplantation embryo, and prevent their degradation or activation. In contrast to other members of the family, does not show protein-arginine deiminase activity due to its inability to bind Ca(2+).
Protein Name Inactive Protein-Arginine Deiminase Type-6
Peptidyl Arginine Deiminase-Like Protein
Peptidylarginine Deiminase Vi
Hpadvi
Protein-Arginine Deiminase Type Vi
Protein-Arginine Deiminase Type-6
Database Links Reactome: R-HSA-3247509
Cellular Localisation Cytoplasm
Cytoplasmic Vesicle
Secretory Vesicle
Cortical Granule
Nucleus
Core Component Of Cytoplasmic Lattices In Oocytes
Also Nuclear
Alternative ELISA Names Inactive Protein-Arginine Deiminase Type-6 ELISA kit
Peptidyl Arginine Deiminase-Like Protein ELISA kit
Peptidylarginine Deiminase Vi ELISA kit
Hpadvi ELISA kit
Protein-Arginine Deiminase Type Vi ELISA kit
Protein-Arginine Deiminase Type-6 ELISA kit
PADI6 ELISA kit
PAD6 ELISA kit
output

Information sourced from Uniprot.org

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