Human PADI6 (Peptidyl Arginine Deiminase Type VI) Sandwich ELISA Kit Kit (STJE0011247)

Human PADI6 (Peptidyl Arginine Deiminase Type VI) Sandwich ELISA Kit Kit (STJE0011247)

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STJE0011247
£465.50 - £636.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.062ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This PADI6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: PADI6
Gene ID: 353238
Uniprot ID: PADI6_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in oocytes and weakly expressed in other somatic tissues.
Post Translational Modifications Phosphorylation at Ser-10, possibly by RSK-type kinases, and Ser-446 creates binding sites for 14-3-3 proteins.
Function Catalyzes the deimination of arginine residues of proteins. May be involved in cytoskeletal reorganization in the egg and early embryo. Catalyzes the deimination of arginine residues of proteins. In oocytes, is released during cortical reaction and plays a role in preimplantation cleavage and early embryonic development. May be involved in cytoskeletal reorganization in the egg and early embryo.
Protein Name Protein-Arginine Deiminase Type-6
Peptidyl Arginine Deiminase-Like Protein
Peptidylarginine Deiminase Vi
Hpadvi
Protein-Arginine Deiminase Type Vi
Database Links Reactome: R-HSA-3247509
Cellular Localisation Cytoplasm
Nucleus
Cytoplasmic Vesicle
Secretory Vesicle
Cortical Granule
Predominantly Cytoplasmic (Oocyte Cytoplasmic Sheets)
Also Nuclear
Released Extracellularly During The Cortical Reaction
And Remains Associated With The Blastomeres Surfaces As A Peripheral Membrane Protein Until The Blastocyst Stage Of Development
Alternative ELISA Names Protein-Arginine Deiminase Type-6 ELISA kit
Peptidyl Arginine Deiminase-Like Protein ELISA kit
Peptidylarginine Deiminase Vi ELISA kit
Hpadvi ELISA kit
Protein-Arginine Deiminase Type Vi ELISA kit
PADI6 ELISA kit
PAD6 ELISA kit
output

Information sourced from Uniprot.org

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