| Short Description : | Recombinant-Human PACC1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | Please contact us for further information. |
| Gene Symbol: | PACC1 |
| Gene ID: | 55248 |
| Uniprot ID: | PACC1_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | His98-Ala301 |
| Post Translational Modifications | N-glycosylated. |
| Function | Chloride channel gated by pH that facilitates the entry of chloride ions into cells upon exposure to extracellular acidic pH. Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling. |
| Protein Name | Proton-Activated Chloride ChannelPacHpacAcid-Sensitive Outwardly-Rectifying Anion ChannelAsorProton-Activated Outwardly Rectifying Anion ChannelPaoracTransmembrane Protein 206Htmem206 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Proton-Activated Chloride Channel proteinPac proteinHpac proteinAcid-Sensitive Outwardly-Rectifying Anion Channel proteinAsor proteinProton-Activated Outwardly Rectifying Anion Channel proteinPaorac proteinTransmembrane Protein 206 proteinHtmem206 proteinPACC1 proteinC1orf75 proteinTMEM206 protein |
Information sourced from Uniprot.org